Potential Antitumor Agents. 55. 6-Phenylphenanthridine-4-carboxamides: A New Class of DNA-Intercalating Antitumor Agents

DOI: 10.1021/jm00399a015

Source and publish data:

Journal of Medicinal Chemistry p. 774 - 779 (1988)

Update date:2022-09-26

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Authors:

Atwell, Graham J.

Baguley, Bruce C.

Denny, William A.

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Article abstract of DOI:10.1021/jm00399a015

Derivatives of the DNA-intercalating agent N-<2-(dimethylamino)ethyl>phenanthridine-4-carboxamide (7) have been prepared and shown to have moderate in vivo antitumor activity against both the P388 leukemia and Lewis lung carcinoma.This demonstrates that t

Full text of DOI:10.1021/jm00399a015

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