
Chemistry Letters p. 887 - 890 (1987)
Update date:2022-09-26
Topics:
Suzuki, Hitomi
Yi, Qui
Inoue, Junko
Kusume, Kumiko
Ogawa, Takuji
Copper(I) iodide-catalyzed reaction of aryl iodides with anion derived from phenylsulfonylacetonitrile in hot hexamethylphosphoric triamide affords α-arylated nitriles in good to moderate yields.Further alkylation of these nitriles followed by reductive removal of sulfonyl group provides a simple route to α-arylalkanenitriles.
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