Tetrahedron Letters p. 8159 - 8162 (1992)
Update date:2022-08-04
Topics:
Casy, Guy
The enantioselective reduction 2,4-dioxo acids catalysed by lactate dehydrogenases provided access to 2-hydroxy-4-oxo acids of both S and R configuration. Subsequent diastereoselective chemical reduction affords 4-substituted 2-hydroxybutyrolactones.
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