Organocatalytic asymmetric syn-aldol reactions of aldehydes with long-chain aliphatic ketones on Water and with dihydroxyacetone in organic solvents

DOI: 10.1002/adsc.200800105

Source and publish data:

Advanced Synthesis and Catalysis p. 1390 - 1396 (2008)

Update date:2022-09-26

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Authors:

Zhu, Ming-Kui

Xu, Xiao-Ying

Gong, Liu-Zhu

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Article abstract of DOI:10.1002/adsc.200800105

An on-water, asymmetric, and direct synaldol reaction of aliphatic ketones with aromatic aldehydes catalyzed by a primary amino acid-based organocatalyst afforded the syn-aldol adducts in high yields with excellent diastereo- and enantioselectivities (up

Full text of DOI:10.1002/adsc.200800105

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