Synthesis of 7-Substituted Indolactam-V. An Introduction of Hydrophobic Moieties on the Indole Ring.

Article abstract of DOI:10.1016/S0040-4020(01)86807-1

(-)-Indolactam-V, which shares the same partial stucture of teleocidins A and B, shows a weak promoting activity compared to teleocidins.It suggests that the hydrophobic moieties substituted on the 6,7-positions of teleocidins play a role in increasing th