Tetrahedron Letters p. 363 - 366 (1989)
Update date:2022-09-26
Topics:
Takeda, Hideo
Tachinami, Takeshi
Aburatani, Masakazu
Takahashi, Hisashi
Morimoto, Toshiaki
Achiwa, Kazuo
The neutral (2S,4S)-MCCPM-rhodium complex was found to be an efficient catalyst for asymmetric hydrogenation of α-aminoacetophenone derivatives.A practical asymmetric synthesis of (S)-(-)-levamisole was realized by using this hydrogenation as a key reaction.
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