Journal of Medicinal Chemistry p. 870 - 874 (1988)
Update date:2022-07-29
Topics: Peptide Derivatives Antimalarial Agents Antimalarial Experimental Peptide Derivatives
Philip, Abraham
Kepler, John A.
Johnson, Bernadette H.
Carroll, F. Ivy
Three peptide derivatives of primaquine were synthesized.The compounds were tested for radical curative antimalarial activity against Plasmodium cynomolgi in rhesus monkeys and blood schizonticidal antimalarial activity against Plasmodium berghei in mice.
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