Peptide Derivatives of Primaquine as Potential Antimalarial Agents

DOI: 10.1021/jm00399a032

Source and publish data:

Journal of Medicinal Chemistry p. 870 - 874 (1988)

Update date:2022-07-29

Topics: Peptide Derivatives Antimalarial Agents Antimalarial Experimental Peptide Derivatives

Authors:

Philip, Abraham

Kepler, John A.

Johnson, Bernadette H.

Carroll, F. Ivy

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Article abstract of DOI:10.1021/jm00399a032

Three peptide derivatives of primaquine were synthesized.The compounds were tested for radical curative antimalarial activity against Plasmodium cynomolgi in rhesus monkeys and blood schizonticidal antimalarial activity against Plasmodium berghei in mice.

Full text of DOI:10.1021/jm00399a032

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