A FACILE AND ALTERNATIVE SYNTHESIS OF QUINOLINE NUCLEUS USING THERMAL CYCLIZATION OF 2-AZAHEXATRIENE SYSTEM GENERATED FROM 2-ALKENYL ACYLANILINE WITH POCl3

DOI: 10.3987/R-1987-07-1883

Source and publish data:

Heterocycles p. 1883 - 1889 (1987)

Update date:2022-07-29

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Authors:

Hibino, Satoshi

Sugino, Eiichi

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Article abstract of DOI:10.3987/R-1987-07-1883

The thermal cyclization of 2-alkenyl acylanilines with POCl3 in toluene or xylene gave quinoline derivatives in good yield via 2-azahexatriene system in situ.

Full text of DOI:10.3987/R-1987-07-1883

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