Synthetic studies towards the identification of novel capuramycin analogs with mycobactericidal activity

DOI: 10.3987/COM-08-S(F)38

Source and publish data:

Heterocycles p. 217 - 225 (2009)

Update date:2022-07-30

Topics:

Authors:

Kurosu, Michio

Li, Kai Li, Kai

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Article abstract of DOI:10.3987/COM-08-S(F)38

Expeditious syntheses of capuramycin, an effective MraY inhibitor in vivo, analogs are described. Synthetic schemes reported here are extremely useful for the generation of capuramycin analogs to identify minimum structure requirement to exhibit antimycobactericidal activity.

Full text of DOI:10.3987/COM-08-S(F)38

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