Bioorganic and Medicinal Chemistry Letters p. 976 - 980 (2009)
Update date:2022-08-05
Topics:
Sparks, Steven M.
Banker, Pierette
Bickett, David M.
Carter, H. Luke
Clancy, Daphne C.
Dickerson, Scott H.
Dwornik, Kate A.
Garrido, Dulce M.
Golden, Pamela L.
Nolte, Robert T.
Peat, Andrew J.
Sheckler, Lauren R.
Tavares, Francis X.
Thomson, Stephen A.
Wang, Liping
Weiel, James E.
Optimization of the amino acid residue within a series of anthranilimide-based glycogen phosphorylase inhibitors is described. These studies culminated in the identification of anthranilimides 16 and 22 which displayed potent in vitro inhibition of GPa in
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