SYNTHESIS OF INDOLIZINES STARTING FROM PYRYLIUM SALTS

Article abstract of DOI:10.1016/S0040-4039(00)96307-X

β-N-Pyridinium acetaldehydes with alkyl substituents in the 2 and 6 positions of the pyridinium ring, obtained from the corresponding pyrylium salts, cyclise in alkaline medium to new indolizines.This high-yield reaction sequence is optimal for indolizines unsubstituted in the five membered ring which are difficultly accessible by other methods.