Synthesis and estrogen receptor selectivity of 1,1-bis(4-hydroxyphenyl)-2-(p-halophenyl)ethylenes

DOI: 10.1021/jm00402a037

Source and publish data:

Journal of Medicinal Chemistry p. 1471 - 1475 (1988)

Update date:2022-08-02

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Authors:

Ruenitz Ruenitz

Bagley Bagley

Nanavati

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Article abstract of DOI:10.1021/jm00402a037

A series of triarylethylenes (1a-e) were synthesized and evaluated for their ability to compete with [³H]estradiol for high-affinity estrogen receptors (ER) in immature rat uterine cytosol. All compounds showed affinity comparable to that of es

Full text of DOI:10.1021/jm00402a037

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