High regio- and stereoselective synthesis of (Z)- or (E)-N-acryl butenedioic monoimide derivatives by a multicomponent reaction

Article abstract of DOI:10.1055/s-0028-1083323

An efficient synthesis of (Z)- or (E)-N-acryl butenedioic monoimide derivatives with high regio- and stereoselectivity by the multicomponent reaction of acetylenic esters/ketones, isocyanides, and carboxylic acids is described. The E-isomers, obtained in