AMINO ACID DERIVATIVES THAT STABILIZE SECONDARY STRUCTURES OF POLYPEPTIDES-III. β-ENAMINONITRILES AS ANALOGS OF SECONDARY AMIDES. THE MCC GROUP-1-ACYLAMINO-2-AMINOALKYL-3-CYANO-2-CYCLOPENTENES AS AMINO ACID ANALOGS.

Article abstract of DOI:10.1016/S0040-4039(00)96585-7

The properties of β-cyanoenamines as analogs of amides are studied with derivatives of a rigid amino acid equivalent-Mcc=1,2-diamino-3-cyanocyclopentene, prepared in two steps from methyl 2-(N-Boc-amino)-5-cyclopentanoate.Racemation of Mcc and incorporati