Journal of Medicinal Chemistry p. 1625 - 1628 (1988)
Update date:2022-07-30
Topics:
Thurkauf
Hillery
Mattson
Jacobsen
Rice
The cis and trans enantiomers of the 1-(1-phenyl-3-methylcyclohexyl)piperidines were prepared from either 3(R)- or 3(S)-methylcyclohexanone through the Bruylents reaction or a modified azide route, respectively. Separation of the intermediate amines (5 an
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