Synthesis and Antiviral Activity of 9-Alkoxypurines. 2. 9-(2,3-Dihydroxypropoxy)-, 9-(3,4-Dihydroxybutoxy)-, and 9-(1,4-Dihydroxybut-2-oxy)purines

DOI: 10.1021/jm00105a010

Source and publish data:

Journal of Medicinal Chemistry p. 57 - 65 (1991)

Update date:2022-08-03

Topics:

Authors:

Bailey, Stuart

Harnden, Michael R.

Jarvest, Richard L.

Parkin, Ann

Boyd, Malcolm R.

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Article abstract of DOI:10.1021/jm00105a010

Reaction of alkenoxyamines (3, 5) or (R,S)-, (R)-, and (S)-hydroxy-protected derivatives of hydroxyalkoxyamines (20a,b, 37a-c) with 4,6-dichloro-2,5-diformamidopyrimidine (4) and cyclization of the resultant 6-<(alkenoxy)amino>- and 6-(alkoxyamino)pyrimid

Full text of DOI:10.1021/jm00105a010

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