Addition of Twisted 1-Thioacetyl-2,2-diaminoethylenes to Dimethyl Acetylenedicarboxylate. Formation and Ring Opening of Thiopyran-4-spiro-2'-(1',3'-diazacyclanes)

DOI: 10.1021/jo00005a043

Source and publish data:

Journal of Organic Chemistry p. 1902 - 1907 (1991)

Update date:2022-07-29

Topics: Addition reaction Chromatography Recrystallization Nucleophilic Attack Cycloaddition Ring-Opening Reaction Spectroscopic Analysis Thiopyran Spiro compound

Authors:

Khan, Agha Zul-Qarnain

Sandstroem, Jan

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Article abstract of DOI:10.1021/jo00005a043

Reaction of 1,3-dialkyl-2-(4,4-dimethyl-2,6-dithiocyclohexylidene)imidazolidines and -hexahydropyrimidines (twisted push-pull ethylenes, 3) with methyl iodide followed by treatment with base leads smoothly to S-methyl derivatives, which are betaines with

Full text of DOI:10.1021/jo00005a043

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