A facile synthesis of (R)-3-amino-4-phenylbutyric acid from L-aspartic acid

Article abstract of DOI:10.1271/bbb.60.916

A practical synthesis of (R)-3-amino-4-phenylbutyric acid 1, based on Friedel-Crafts acylation with the α-aminocarboxyl group of L- aspartic acid retaining its original α-carbon chirality, is described.

Full text of DOI:10.1271/bbb.60.916

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A Facile Synthesis of (R)-3-Amino-4-phenylbutyric
Acid from L-Aspartic Acid
Masahiko Sekia & Kazuo Matsumotoa
a Lead Optimization Research Laboratory, Tanabe Seiyaku Co., Ltd., 16–89, Kashima
3–chome, Yodogawa-ku, Osaka 532, Japan
Published online: 12 Jun 2014.
To cite this article: Masahiko Seki & Kazuo Matsumoto (1996) A Facile Synthesis of (R)-3-Amino-4-phenylbutyric Acid from
L-Aspartic Acid, Bioscience, Biotechnology, and Biochemistry, 60:5, 916-917, DOI: 10.1271/bbb.60.916
To link to this article: http://dx.doi.org/10.1271/bbb.60.916
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