Synthesis and biological evaluation of quinocarcin derivatives: Thioalkyl-substituted quinones and hydroquinones

Article abstract of DOI:10.1021/jm00111a006

Varieties of thioalkyl-containing quinone and hydroquinone analogues of quinocarcin (1a) were prepared effectively, by addition of mercaptan to 3a-c, which were derived from 1a via DX-52-1 (1b). Antitumor activities of these analogues were preliminarily e