A Stereocontrolled Synthesis of 2,3,5-Trisubstituted Tetrahydrofurans from Aldolized γ-Diketones via Cyclization-reduction Process

DOI: 10.1246/cl.1986.1157

Source and publish data:

Chemistry Letters p. 1157 - 1160 (1986)

Update date:2022-08-03

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Authors:

Mukaiyama, Teruaki

Hayashi, Masaji

Ichikawa, Junji

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Article abstract of DOI:10.1246/cl.1986.1157

2,3,5-Trisubstituted tetrahydrofurans with cis-2,5 relationship are obtained in good yields by cyclization of the silyl ethers of aldolized γ-diketones followed by successive stereocontrolled reduction with triethylsilane in the presence of trityl perchlo

Full text of DOI:10.1246/cl.1986.1157

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