Fused Pyrimidines by a Tandem Aza-Wittig / Electrocyclic Ring Closure Strategy: Synthesis of Pyrazolo pyrimidyne, Triazolo pyrimidyne, and Thiazolo pyrimidyne Derivatives

Article abstract of DOI:10.1021/jo00255a003

The aza-Wittig reaction of iminophosphoranes derived from 5-azido -4-formylazoles or 4-azido-5-formylazoles with heterocumulenes leads to functionalized fused pyrimidines.Iminophosphoranes 12, derived from 5-azido-4-formylpyrazole, react under mild condit