Tetrahedron Letters p. 5395 - 5398 (1987)
Update date:2022-09-26
Topics:
McCombie, S. W.
Nagabhushan, T. L.
N-Benzoylcarbamates formed in situ from 2,3-epoxyalcohols and PhCONCO undergo clean to C-2 cyclisation followed by N to O acyl migration on treatment with catalytic sodium imidazolide or other bases.Subsequent benzoate cleavage (NaOMe) is accompanied by equilibration of the N-unsubstituted oxazolidinones; cleavage without significant isomerisation is achieved with MeLi or Zn(BH4)2.This methodology is applied in a diastereospecific, 6-step conversion of methyl 4-bromophenyl sulfonate to racemic Thiamphenicol.
View MoreZibo Kunran Enterprises Co. LTD
website:http://www.kunranchem.com
Contact:0086 533 5200669
Address:No. 96 Jinjing Avenue, Zibo, Shandong, China
Ningbo Distant Chemicals Co.,Ltd
Contact:86-574-27862490,27862438
Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
Jinan Decheng Hemu Medical Technology Co.，Ltd.
Contact:+86-531-68650525
Address:NO.554 Zhengfeng Road High-new Technology Development Zone
Yancheng Creator Chemical Co., Ltd
Contact:0086-515-88710008 88710068 88710858 88710868
Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Doi:10.1016/j.tetasy.2014.06.008
(2014)Doi:10.1021/acs.orglett.5b01737
(2015)Doi:10.1021/ic202435r
(2012)Doi:10.1039/c5cc05740j
(2015)Doi:10.1016/j.ejmech.2008.06.027
(2009)Doi:10.1016/j.ejmech.2014.04.046
(2014)
