IMPROVED PREPARATION OF 5-HYDROXYPROTOBERBERINE DERIVATIVES VIA 3-ARYLTETRAHYDROISOQUINOLINES

DOI: 10.1016/S0040-4020(01)85107-3

Source and publish data:

Tetrahedron p. 203 - 208 (1988)

Update date:2022-07-29

Topics:

Authors:

Dominguez, E.

Badia, M. D.

Castedo, L.

Dominguez, D.

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Article abstract of DOI:10.1016/S0040-4020(01)85107-3

A regioselective synthetic pathway is reported to prepare 5-hydroxytetrahydroprotoberberines, starting from readily avaiable isoquinoline derivatives.Bromoacetaldehyde diethyl acetal is found to be an effective and convenient reagent for N-alkylation of t

Full text of DOI:10.1016/S0040-4020(01)85107-3

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Product name:trans-3-(3,4-dimethoxyphenyl)-6,7,8-trimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline

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