AN EXPEDITIOUS SYNTHESIS OF A 1Β-METHYLCARBAPENEM KEY INTERMEDIATE

DOI: 10.1016/0040-4039(88)80016-9

Source and publish data:

Tetrahedron Letters p. 61 - 64 (1988)

Update date:2022-08-04

Topics:

Authors:

Deziel, Robert

Endo, Masaki

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Article abstract of DOI:10.1016/0040-4039(88)80016-9

The β-methylcarbapenem key intermediate 4 was prepared via a novel aldol-type alkylation of 2 with the divalent tin enolate 6 generated in situ from 7 and metallic tin.

Full text of DOI:10.1016/0040-4039(88)80016-9

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