Bioorganic and Medicinal Chemistry Letters p. 2591 - 2594 (2009)
Update date:2022-08-03
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The synthesis, SAR and binding affinities are described for cannabinoid-1 receptor (CB1R) specific inverse agonists based on pyridopyrimidine and heterotricyclic scaffolds. Food intake and pharmacokinetic evaluation of several of these compounds indicate
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(2009)
