1,1,1,3,3,3-HEXAFLUORO-2-PROPYL GROUP AS A NEW PHOSPHATE PROTECTING GROUP FOR OLIGORIBONUCLEOTIDE SYNTHESIS IN THE PHOSPHOTRIESTER APPROACH

DOI: 10.1016/S0040-4020(01)89492-8

Source and publish data:

Tetrahedron p. 5459 - 5468 (1989)

Update date:2022-08-05

Topics:

Authors:

Yamakage, Shunichi

Fijii, Masayo

Takaku, Hiroshi

Uemura, Masaru

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Article abstract of DOI:10.1016/S0040-4020(01)89492-8

The 1,1,1,3,3,3-Hexafluoro-2-propyl group can be used as a new class of phosphate protecting group for the protecting group of internucleotidic bonds in the oligonucleotide synthesis by the phosphotriester approach.This protecting group is removed easily

Full text of DOI:10.1016/S0040-4020(01)89492-8

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