Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies

DOI: 10.1016/j.bioorg.2015.07.001

Source and publish data:

Bioorganic Chemistry p. 22 - 29 (2015)

Update date:2022-07-30

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Authors:

Mathew, Bijo

Mathew, Githa Elizabeth

U?ar, Gülberk

Baysal, Ipek

Suresh, Jerad

Vilapurathu, Jobin Kunjumon

Prakasan, Aneesh

Suresh, Jeethu Kuruppath

Thomas, Anjana

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Article abstract of DOI:10.1016/j.bioorg.2015.07.001

A series of methoxylated chalcones with fluoro and trifluoromethyl derivatives were synthesized and investigated for their ability to inhibit human monoamine oxidase A and B. The chemical structures of the compounds have been characterized by means of the

Full text of DOI:10.1016/j.bioorg.2015.07.001

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