Reaction of Acylketene S,N-Acetals with Malonyl Chloride: Synthesis of Novel 1,5-Substituted 4-Hydroxy-6-methylthio-2(1H)-pyridones and 6,8-Substituted 4-Hydroxy-7-methylthio-2,5-dioxo-5,6-dihydro-2H-pyrano pyridines

DOI: 10.1055/s-1988-27476

Source and publish data:

Synthesis p. 87 - 89 (1988)

Update date:2022-08-05

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Authors:

Chakrasali, R. T.

Ila, H. Ila, H.

Junjappa, H.

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Article abstract of DOI:10.1055/s-1988-27476

The acylketene S,N-acetals 1 react with one equivalent of malonyl chloride in the presence of triethylamine to give novel 1,5-substituted 4-hydroxy-6-methylthio-2(1H)-pyridones 3 in good yields.However, in the presence of excess of malonyl chloride (three

Full text of DOI:10.1055/s-1988-27476

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