Anion-Receptor Molecules: Synthesis of a Chiral and Functionalized Binding Subunit, a Bicyclic Guanidinium Group Derived from L- or D-Asparagine

Article abstract of DOI:10.1002/hlca.19880710402

The optically active (4S,8S)-4,8-bis(hydroxymethyl)-1,5,7-triazabicyclo<4.4.0>dec-5-ene ((S,S)-1) has been synthesized in nine steps from L-asparagine with a total yield of 5.1percent.Similarly, the enantiomer (R,R)-1 has been prepared from D-asparagine,