Journal of Organic Chemistry p. 1936 - 1938 (1986)
Update date:2022-09-26
Topics:
Meyers, A. I.
Lefker, Bruce A.
Wanner, Klaus Th.
Aitken, R. Alan
An efficient approach to the title compounds in > 95percent ee has been accomplished by metalation and alkylation of chiral bicyclic lactams derived from δ-keto acids and (1S,2S)-2-amino-1-phenyl-1,3-propanediol.
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