Chemical and biological investigation of cyclopropyl containing diaryl-pyrazole-3-carboxamides as novel and potent cannabinoid type 1 receptor antagonists

DOI: 10.1021/jm900179y

Source and publish data:

Journal of Medicinal Chemistry p. 4329 - 4337 (2009)

Update date:2022-08-04

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Authors:

Szabó, Gyorgy

Varga, Balázs

Páyer-Lengyel, Dóra

Szemzo, Attila

Erdélyi, Péter

Vukics, Krisztina

Szikra, Judit

Hegyi, éva

Vastag, Mónika

Kiss, Béla

Laszy, Judit

Gyertyán, István

Fischer, János

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Article abstract of DOI:10.1021/jm900179y

Obesity is a major clinical problem in the western world, and many molecular targets have been explored in the search for effective therapeutic agents. One of these, antagonism of the cannabinoid 1 (CB1) receptor, rose to prominence following reports demo

Full text of DOI:10.1021/jm900179y

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