Mitomycin C analogues with a substituted hydrazine at position 7. Synthesis, spectral properties, and biological activity

DOI: 10.1021/jm00121a044

Source and publish data:

Journal of Medicinal Chemistry p. 248 - 252 (1989)

Update date:2022-08-02

Topics:

Authors:

Sawhney Sawhney

Kohn Kohn

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Article abstract of DOI:10.1021/jm00121a044

A select number of mitomycin C derivatives with a substituted hydrazine group at position 7 were synthesized and tested for antineoplastic activity by using an in vivo test with murine P388 leukemia. Several of the adducts displayed activity comparable to

Full text of DOI:10.1021/jm00121a044

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