Journal of Organic Chemistry p. 5491 - 5501 (1988)
Update date:2022-08-02
Topics: Stereoselective Intramolecular N-Protected 3-Hydroxy-4-pentenylamines 4-Hydroxy-5-hexenylamines
Tamaru, Yoshinao
Kawamura, Shin-ichi
Bando, Takashi
Tanaka, Kunitada
Hojo, Makoto
Yoshida, Zen-ichi
Haloamidation of N-(p-tolylsulfonyl)-3-hydroxy-4-pentenylamines proceeds regio- and stereoselectively to provide cis-2-(halomethyl)-3-hydroxypyrrolidines in high yields.The tosylamides with phenyl and dimethyl substituents at C-5 cyclize to give six-membe
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(1988)
