METALATIONS OF IMIDAZOLES. (POLY)FUNCTIONALIZATION AND CONVERSIONS TO IMIDAZOLONES

DOI: 10.1016/0040-4039(88)85176-1

Source and publish data:

Tetrahedron Letters p. 3411 - 3414 (1988)

Update date:2022-08-02

Topics:

Authors:

Lipshutz, Bruce H.

Huff, Bret

Hagen, William

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Article abstract of DOI:10.1016/0040-4039(88)85176-1

N-SEM protected imidazoles can be sequentially derivatized at the 2- and then 5-positions in a 1-pot operation.Quenching with selected peroxides following initial lithiation leads directly to imidazolones.

Full text of DOI:10.1016/0040-4039(88)85176-1

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