An alternative synthesis of Tamiflu: a synthetic challenge and the identification of a ruthenium-catalyzed dihydroxylation route

DOI: 10.1016/j.tet.2009.05.077

Source and publish data:

Tetrahedron p. 6017 - 6024 (2009)

Update date:2022-07-31

Topics:

Authors:

Yamatsugu, Kenzo

Kanai, Motomu

Shibasaki, Masakatsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.tet.2009.05.077

Synthetic studies of Tamiflu and the identification of a ruthenium-catalyzed dihydroxylation route are disclosed. This newly developed synthetic process circumvents the need for a Mitsunobu inversion step and the use of explosive reagents. This

Full text of DOI:10.1016/j.tet.2009.05.077

Products guided by the article

Product name:C₂₅H₃₆N₄O₆Si

Cas No:1184177-17-0

R&D Labs maybe for 1184177-17-0

Jiaxing Taixin Pharmaceutical Chemical Co., Ltd

Contact:0573-82613601

Address:Chemical Park, Jiaxing, Zhejiang, China
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China
Zibo Xiaoguang Chemical Material Co., Ltd

Contact:15954099116

Address:Boshan Development Zone
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao
XZL BIO-TECHNOLOGY CO., LTD.

Contact:0086 533 2282832

Address:Zibo，Shandong

Relevant to this article

Palladium-catalyzed carbonylation of halo arene-cis-dihydrodiols to the corresponding carboxylates. Access to compounds unavailable by toluene dioxygenase-mediated dihydroxylation of the corresponding benzoate esters

Doi:10.1039/c4ob01417k
(2014)
Antitumor and antiviral activity of synthetic α- and β-ribonucleosides of certain substituted pyrimido[5,4-d]pyrimidines: a new synthetic strategy for exocyclic aminonucleosides

Doi:10.1021/jm00123a022
(1989)
Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the α6^* subtype

Doi:10.1016/j.bmcl.2009.05.085
(2009)
Isocyanide-based MCRs: Diastereoselective cascade synthesis of perfluoroalkylated pyrano[3,4-c]pyrrole derivatives

Doi:10.1016/j.jfluchem.2021.109723
(2021)
A new synthesis of 6-arylamino-2-heteroarylimino-1,2-dihydro-1,3,5-triazines from 2,4-bis(heteroarylimino)-1,3-diazetidines and amidines

Doi:10.1055/s-1988-27498
(1988)
A ROUTE TO LONG-CHAIN AMINO SUGARS BY THREE SUBSTITUTED THIAZOLES AS AUXILIARIES: THIAZOLE-2-CARBONITRILE N-OXIDE, 2-TRIMETHYLSILYLTHIAZOLE, AND 2-THIAZOLYLMETHYLENETRIPHENYLPHOSPHORANE

Doi:10.1016/S0040-4020(01)85954-8
(1988)

Article Doi