SYNTHESIS OF CHEMICALLY REACTIVE ANALOGUES OF AZT AND THEIR BIOLOGICAL EVALUATION AGAINST HIV

DOI: 10.1016/0040-4039(88)85124-4

Source and publish data:

Tetrahedron Letters p. 3211 - 3214 (1988)

Update date:2022-09-26

Topics:

Authors:

Schreiber, Stuart L.

Ikemoto, Norihiro

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Article abstract of DOI:10.1016/0040-4039(88)85124-4

Several 3'-deoxythymidine analogues were prepared and tested against HIV.The choice of analogues was based on their possible covalent binding to the enzyme reverse transcriptase.

Full text of DOI:10.1016/0040-4039(88)85124-4

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