Journal of Medicinal Chemistry p. 361 - 367 (1992)
Update date:2022-08-04
Topics:
Sanchez
Bridges
Bucsh
Domagala
Gogliotti
Hagen
Heifetz
Joannides
Sesnie
Shapiro
Szotek
A series of 8-(trifluoromethyl)-substituted quinolones has been prepared and evaluated for in vitro and in vivo antibacterial activity, and phototolerance in a mouse phototolerance assay. These analogues were compared to the corresponding series of 6,8-di
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