1,2-ADDITION OF α-AMINO ACID DERIVATIVES TO CONJUGATED ALDEHYDES: SYNTHESIS OF β-SUBSTITUTED SERINES

DOI: 10.1016/0040-4039(88)85098-6

Source and publish data:

Tetrahedron Letters p. 3109 - 3110 (1988)

Update date:2022-07-29

Topics: Characterization Reagents Isolation and Purification Reaction Mechanism

Authors:

Dikshit, Dinesh K.

Singh, Sangeeta

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Article abstract of DOI:10.1016/0040-4039(88)85098-6

Reaction of C,N-dianions of N-acyl α-amino acid esters with conjugated aldehydes at -78 deg C give threo and erythro-β-substituted serine derivates in excellent yields.

Full text of DOI:10.1016/0040-4039(88)85098-6

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