A study of the synthesis and antiarrhythmic properties of selected 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2,4-positions and at the 9-position

DOI: 10.1016/0223-5234(90)90158-Y

Source and publish data:

European Journal of Medicinal Chemistry p. 1 - 8 (1990)

Update date:2022-09-26

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Authors:

Smith Smith

Thompson

Berlin Berlin

Holt Holt

Scherlag

Patterson

Lazzara Lazzara

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Article abstract of DOI:10.1016/0223-5234(90)90158-Y

Some members of the family of 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2-, 4- and 9-positions were synthesized via a Mannich reaction. Hearts of anesthetized dogs with myocardial infarctions were subjected to ventricular tachycardia (VT)

Full text of DOI:10.1016/0223-5234(90)90158-Y

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