European Journal of Medicinal Chemistry p. 1 - 8 (1990)
Update date:2022-09-26
Topics:
Smith
Thompson
Berlin
Holt
Scherlag
Patterson
Lazzara
Some members of the family of 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2-, 4- and 9-positions were synthesized via a Mannich reaction. Hearts of anesthetized dogs with myocardial infarctions were subjected to ventricular tachycardia (VT)
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