A New Stereoselective Synthesis of (E,Z)-Conjugated Hydroxy-Dienes, Key Intermediates for the Synthesis of HETES

DOI: 10.1246/cl.1988.1927

Source and publish data:

Chemistry Letters p. 1927 - 1930 (1988)

Update date:2022-08-04

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Authors:

Bloch, Robert

Gasparini, Giovanna

Girard, Christian

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Article abstract of DOI:10.1246/cl.1988.1927

A general and highly stereoselective synthesis of (E,Z)-conjugated hydroxy-dienes is described and its synthetic utility is illustrated by the synthesis of precursors of (+/-)-LTA₄ methyl ester and (+/-)-5-HETE respectively.

Full text of DOI:10.1246/cl.1988.1927

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