RESOLUTION AND DETERMINATION OF ENANTIOMERIC EXCESSES OF CHIRAL ALDEHYDES VIA CHIRAL IMIDAZOLIDINES

DOI: 10.1016/0040-4039(88)85258-4

Source and publish data:

Tetrahedron Letters p. 2677 - 2680 (1988)

Update date:2022-08-05

Topics:

Authors:

Mangeney, P.

Alexakis, A.

Normant, J. F.

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Article abstract of DOI:10.1016/0040-4039(88)85258-4

Enantiomeric purity of chiral aldehydes was determined by NMR analysis of derived imidazolidines.The diastereomeric imidazolidines were easily separated by silica gel column and converted into enantiomerically pure aldehyde by acid hydrolysis.

Full text of DOI:10.1016/0040-4039(88)85258-4

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Product name:3-[3-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-oxiranyl]-propionic acid methyl ester

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