Reaction of 3-Amino-2-alkenimines with Alkali Metals: Unexpected Synthesis of Substituted 4-(Arylamino)quinolines

DOI: 10.1021/jo00272a026

Source and publish data:

Journal of Organic Chemistry p. 2596 - 2598 (1989)

Update date:2022-07-29

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Authors:

Barluenga, Jose

Aguilar, Enrique

Joglar, Jesus

Olano, Bernardo

Fustero, Santos

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Article abstract of DOI:10.1021/jo00272a026

A study of the reduction of 3-amino-2-alkenimines 1 with alkali metals is reported.The nature of the alkali metal plays an important role in the course of the process.In this context, a new and simple method for the regioselective synthesis of 4-(arylamino)quinolines 4 from 1 and sodium or potassium is described.

Full text of DOI:10.1021/jo00272a026

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