
Journal of Organic Chemistry p. 9140 - 9151 (2009)
Update date:2022-08-03
Topics:
Zhang, Jianmin
Polishchuk, Elena A.
Chen, Jie
Ciufolini, Marco A.
(Chemical Equation Presented) The preparation of 4-carbethoxy-5-methyl-2- (phenylsulfonyl)methyloxazole and its use in the elaboration of more complex oxazoles are described. A total synthesis of the unique natural products siphonazoles A and B, illustrates an application of this building block. A discussion of the biological activity of the siphonazoles is also presented.
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