Tetrahedron Letters p. 4303 - 4304 (1988)
Update date:2022-09-26
Topics:
Ohta, Tomihisa
Kimura, Toshihiko
Sato, Nobuaki
Nozoe, Shigeo
Regioselective mono-addition of lithium enolate of esters to N-carbamoyl-L-pyroglutamates (1) gave excellent yields of (2S)-5-oxoamino acid derivatives (2) which were found to be an effective synthon for syntheses of carbapenams and carbapenems.
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Doi:10.1021/jo900573v
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