Synthesis of novel 5-fluoro analogues of norfloxacin and ciprofloxacin

DOI: 10.1021/jm00126a028

Source and publish data:

Journal of Medicinal Chemistry p. 1313 - 1318 (1989)

Update date:2022-09-26

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Authors:

Moran Moran

Ziegler Jr.

Dunne Dunne

Kuck Kuck

Lin Lin

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Article abstract of DOI:10.1021/jm00126a028

A series of polyfluoro-3-quinolonecarboxylic acids have been synthesized and their in vitro antibacterial activity evaluated. The desired 7-(substituted amino) derivatives were prepared from the 5,6,7,8-tetrafluoroquinolone acids. Conversely, amine displa

Full text of DOI:10.1021/jm00126a028

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