Synthesis of novel 5-fluoro analogues of norfloxacin and ciprofloxacin

DOI: 10.1021/jm00126a028

Source and publish data:

Journal of Medicinal Chemistry p. 1313 - 1318 (1989)

Update date:2022-09-26

Topics:

Authors:

Moran Moran

Ziegler Jr.

Dunne Dunne

Kuck Kuck

Lin Lin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00126a028

A series of polyfluoro-3-quinolonecarboxylic acids have been synthesized and their in vitro antibacterial activity evaluated. The desired 7-(substituted amino) derivatives were prepared from the 5,6,7,8-tetrafluoroquinolone acids. Conversely, amine displa

Full text of DOI:10.1021/jm00126a028

Products guided by the article

Product name:ethyl 2,3,4,5,6-pentafluoro-α-<<(4-fluorophenyl)amino>methylene>-β-oxobenzenepropionate

Cas No:119877-53-1

R&D Labs maybe for 119877-53-1

Shanghai PengMo Biotechnology Co.,Ltd

website:http://www.pengmobio.lookchem.com

Contact:86-13052359378

Address:No.218 Hai Qu Road.Shanghai.China
Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Jinan Hongfangde Pharmatech Co.,Ltd

Contact:86-531-88870908

Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD

Contact:+86-571-88932183

Address:Hangzhou
Chengdu King-tiger Pharm-chem. Tech. Co., Ltd

Contact:028-85317716

Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.

Relevant to this article

Ethyl 2-(diisopropoxyphosphoryl)-2h-azirine-3-carboxylate: Reactions with nucleophilic 1,3-dienes

Doi:10.1055/s-0029-1216945
(2009)
N-fusion approach in construction of contracted carbaporphyrinoids: formation of N-fued telluraporphyrin

Doi:10.1002/chem.200900841
(2009)
Total synthesis of "Aliskiren": The first renin inhibitor in clinical practice for hypertension

Doi:10.1021/ol100427v
(2010)
Cyclopropyl carbenoid insertion into alkenylzirconocenes-a convergent synthesis of alkenylcyclopropanes and alkylidenecyclopropanes

Doi:10.1016/j.tetlet.2006.10.132
(2006)
A Mechanistic Study of Halogen Addition and Photoelimination from π-Conjugated Tellurophenes

Doi:10.1021/jacs.5b11649
(2016)
Barium manganate in microwave-assisted oxidation reactions: synthesis of solvatochromic 2,4,6-triarylpyrimidines

Doi:10.1016/j.tetlet.2009.09.116
(2009)

Article Doi