HIGHLY DIASTEREOSELECTIVE INTRAMOLECULAR NITRONE CYCLOADDITIONS TO Α,Β-UNSATURATED ESTERS

DOI: 10.1016/0040-4039(88)85237-7

Source and publish data:

Tetrahedron Letters p. 2881 - 2884 (1988)

Update date:2022-08-04

Topics:

Authors:

Annunziata, Rita

Cinquini, Mauro

Cozzi, Franco

Raimondi, Laura

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Article abstract of DOI:10.1016/0040-4039(88)85237-7

Intramolecular cycloaddition of chiral α-acyloxynitrones to in situ generated α,β-unsaturated esters occurs with very high diastereoselectivity to afford useful precursors for the synthesis of β-lactam antibiotics.

Full text of DOI:10.1016/0040-4039(88)85237-7

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