Synthesis and Reactions of Isoquinoline Derivatives II. Synthesis of 3-Chloroisoquinoline-4-aldehydes

DOI: 10.1055/s-1988-27669

Source and publish data:

Synthesis p. 680 - 683 (1988)

Update date:2022-08-03

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Authors:

Bartmann, W.

Konz, E.

Rueger, W.

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Article abstract of DOI:10.1055/s-1988-27669

1-Aryl-substituted 1,4-dihydro-3(2H)isoquinolinones 1 are easily converted to 1-aryl-3-chloroisoquinoline-4-aldehydes 3 by a two-step procedure involving a Vilsmeier-Haack reaction followed by subsequent oxidation with potassium permanganate under acidic

Full text of DOI:10.1055/s-1988-27669

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