Synthesis and Reactions of Isoquinoline Derivatives II. Synthesis of 3-Chloroisoquinoline-4-aldehydes

DOI: 10.1055/s-1988-27669

Source and publish data:

Synthesis p. 680 - 683 (1988)

Update date:2022-08-03

Topics:

Authors:

Bartmann, W.

Konz, E.

Rueger, W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1988-27669

1-Aryl-substituted 1,4-dihydro-3(2H)isoquinolinones 1 are easily converted to 1-aryl-3-chloroisoquinoline-4-aldehydes 3 by a two-step procedure involving a Vilsmeier-Haack reaction followed by subsequent oxidation with potassium permanganate under acidic

Full text of DOI:10.1055/s-1988-27669

Products guided by the article

Product name:[3-Chloro-6-fluoro-1-(2-fluoro-phenyl)-1H-isoquinolin-(4Z)-ylidenemethyl]-dimethyl-amine

Cas No:120285-20-3

R&D Labs maybe for 120285-20-3

Guangzhou Chemical Reagent Factory

Contact:+86-20-8435 9820 or 8435 7345

Address:Southern Guangzhou, Guangdong, China
SHIJIAZHUANG AGERUO-BIOTECH CO.LTD

Contact:+86-130-2866-6699

Address:Huaian east Road 158
SHANGHAI BIOSUNDRUG CO.,LTD.

Contact:86-21-34622192，13917187091，21-34622765

Address:No. 500 Caobao Road Shanghai P.R China
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD

Contact:+86-576-88685096

Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china

Relevant to this article

A structural examination of the impact of oxygenated side chains in Ephedra compounds in the catalytic asymmetric addition of diethylzinc to aldehydes

Doi:10.1016/j.tetasy.2009.08.028
(2009)
The synthesis of single enantiomers of trans-alkene containing mycolic acids and related sugar esters

Doi:10.1016/j.tet.2016.08.089
(2016)
High-Affinity Leukotriene Receptor Antagonists. Synthesis and Pharmacological Characterization of 2-Hydroxy-3-<(2-carboxyethyl)thio>-3-<2-(8-phenyloctyl)phenyl>propanoic Acid

Doi:10.1021/jm00389a001
(1987)
<6?+4?>CYCLOADDITIONS OF 5-AZONIAFULVENE IONS WITH NITRONES AND AZOMETHINE IMINES.

Doi:10.1016/S0040-4039(00)80510-9
(1988)
Discovery and synthesis of cyclohexenyl derivatives as modulators of CC chemokine receptor 2 activity

Doi:10.1016/j.bmcl.2015.11.051
(2016)
Mixed-metal assemblies based on cyanide-bridged cubane-type Mo ₃CuS₄/Mo₃S₄ clusters and molybdenum carbonyls

Doi:10.1021/ic9002302
(2009)

Article Doi