Polypharmacology of N6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide (IB-MECA) and Related A3 Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPARδ Antagonist Activity Suggests Their

DOI: 10.1021/acs.jmedchem.7b00805

Source and publish data:

Journal of Medicinal Chemistry p. 7459 - 7475 (2017)

Update date:2022-08-15

Topics:

Authors:

Yu, Jinha

Ahn, Seyeon

Kim, Hee Jin

Lee, Moonyoung

Ahn, Sungjin

Kim, Jungmin

Jin, Sun Hee

Lee, Eunyoung

Kim, Gyudong

Cheong, Jae Hoon

Jacobson, Kenneth A.

Jeong, Lak Shin

Noh, Minsoo

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Article abstract of DOI:10.1021/acs.jmedchem.7b00805

A₃ adenosine receptor (AR) ligands including A₃ AR agonist, N⁶-(3-iodobenzyl)adenosine-5′-N-methyluronamide (1a, IB-MECA) were examined for adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs). In

Full text of DOI:10.1021/acs.jmedchem.7b00805

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