Chemistry of Heterocyclic Compounds p. 580 - 586 (1999)
Update date:2022-08-04
Topics:
Modyanova
Duduchava
Piskunkova
Grishina
Terent'ev
Parshikov
Optically active 2-(4-hydroxyphenylcarbamoyloxymethyl)-1-methyl-1,2,5,6-tetrahydropyridine is obtained on microbiological transformation of 1-methyl-2-(N-phenyl-carbamoyloxymethyl)-1,2,5,6-tetrahydropyridine with a growing culture of the fungus C. verticillata VKPM F-430. Transformation of 2-(2-phenylethyl)pyridine by a methanoxidating culture of Methylococcus occurs either by hydroxylation of the side chain or conversion of the substrate into N-oxide, depending on the process conditions. 1999 KluwerAcademic/Plenum Publishers.
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