5-Piperazinylalkyl-2(3H)-oxazolones with Neuroleptic Activity

DOI: 10.1021/jm00130a003

Source and publish data:

Journal of Medicinal Chemistry p. 2241 - 2247 (1989)

Update date:2022-08-04

Topics:

Authors:

Cascio, Giuseppe

Manghisi, Elso

Fregnan, Giancarlo

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Article abstract of DOI:10.1021/jm00130a003

A series of new 4-aryl-5-<ω-(4-aryl-1-piperazinyl)alkyl>-2(3H)-oxazolones was synthesized and tested for neuroleptic activity in mice and rats.Several compounds exhibited interesting neuroleptic activity with very low liability to the extrapyramidal side

Full text of DOI:10.1021/jm00130a003

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